Drug abuse is a disease characterized by continued misuse of drugs even when faced with drug-related job, legal, health, or family difficulties. Problems associated with drug abuse must have existed a minimum of 12 months to meet the diagnosis.

Drug dependence refers to long-term, compulsive drug use, perhaps with attempts to stop but repeatedly returns to drug use. Drug dependence also means that your body has begun to require the drug in higher doses to avoid withdrawal symptoms.

Drug abuse and drug dependence are not terms that should be used to describe people who are taking appropriate dosages of prescribed drugs (pain medication, for example) and who have become physically dependent on them. Diagnosis of both drug abuse and drug dependence requires the presence of specific behavioral symptoms.

Some of the most commonly abused substances include:

  • Cocaine
  • Heroin
  • Morphine
  • LSD
  • Marijuana
  • Sedatives
  • Speed (methamphetamine, “crystal meth”)
  • PCP
  • Ecstasy
  • GHB
  • Ketamine
  • Steroids
  • Inhalants
  • Legal drugs that are used improperly or without a prescription, such as:
    • Narcotic painkillers
    • Amphetamines
    • Drugs for treating anxiety
    • Sleeping pills

The cause of drug abuse and dependence is unknown, although there are a variety of theories. One theory holds that there may be a genetic component that predisposes a person toward using and abusing drugs. Another theory is that drug abuse is a learned behavior and that people begin to use drugs by copying the behavior of those around them. Medical professionals have not been able to target a specific cause.

Brain chemicals may alter the user's perception of the drug's effects. Long-term drug use changes brain function and may reinforce the desire to keep using drugs regardless of the consequences.

Chemical Release in Brain
neurotransmitter
Drugs stimulate unnecessary chemical release in the brain. Used long-term drugs may actually change brain function.
© 2009 Nucleus Medical Media, Inc.